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2′-O-Methyluridine CAS:2140-76-3 Mutengo wemugadziri
2′-O-Methyluridine inyucleoside yakagadziriswa ine boka remethyl panzvimbo ye2′ yeribose ring. Ichinhu chakakosha pakugadzira mamorekuru eRNA akagadziriswa uye yakaongororwa nezvehunhu hwayo hwezvinhu zvehupenyu nehwemishonga. Mamwe emashandisirwo ayo anotaurwa anosanganisira kushandiswa kwayo mukutsvagisa kweRNA, sechikamu mukugadzirwa kweRNA yakagadziriswa yekurapa uye kushanda kwemajini, uye sechishandiso mukudzidza chimiro nekushanda kweRNA.
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4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one CAS:951-77-9
2′-Deoxycytidine inyucleoside inoumbwa nenucleobase cytosine yakabatana neshuga deoxyribose. Ndiyo chinhu chakakosha cheDNA uye inoita basa rakakosha mukuchengetedza nekutumira ruzivo rwemajini mukati mezvisikwa zvipenyu.
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Cytidine-5′-monophosphate (CMP), asidhi yemahara CAS:63-37-6
Cytidine 5'-monophosphate (CMP) inyukleotide inoshanda sechivako chekugadzira nekugadzirisa RNA. Chinhu chakakosha mukuvaka mamorekuru eRNA uye chinobatanidzwa mumabasa akadai se mRNA capping uye nucleotide metabolism. CMP inoshandiswawo mukutsvaga biochemical uye molecular biology kune mashandisirwo akadai se in vitro transcription uye nucleic acid labeling. Basa rayo mu RNA metabolism uye kushandiswa kwayo mumaitiro akasiyana-siyana ekuyedza zvinoita kuti ive chishandiso chakakosha mukunzwisisa chimiro uye basa remamorekuru eRNA.
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IBMX, 3-isobutyl-1-methylxanthine CAS:28822-58-4
3-isobutyl-1-methylxanthine, inozivikanwawo seIBMX, imhando yemethylxanthine inoshandiswa zvakanyanya mukutsvagisa kwesainzi sechinhu chinodzivirira cyclic nucleotide phosphodiesterases. Inozivikanwa nekuwedzera huwandu hwe cyclic AMP (cAMP) uye cyclic GMP (cGMP) mukati memasero nekudzivirira kuputsika kwawo, izvo zvinogona kugadzirisa nzira dzakasiyana dzekutumira masaini mumasero.
Kuwedzera pakushandiswa kwayo mukutsvagisa, IBMX yave ichishandiswa mune dzimwe nzvimbo dzekurapa nekuda kwemhedzisiro yayo yebronchodilator uye vasodilator. Zvisinei, kushandiswa kwayo mukurapa kwevanhu kwakaganhurirwa.
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4-Nitrophenyl phosphate disodium munyu hexahydrate CAS:4264-83-9
4-Nitrophenyl phosphate disodium salt hexahydrate ikemikari inowanzoshandiswa mukutsvakurudza kwemakemikari uye mishonga. Imhando yemunyu ye4-nitrophenyl phosphate, ine maion maviri e sodium uye mamorekuru matanhatu emvura. Iyi kemikari inowanzoshandiswa se substrate yekuongorora phosphatase uye mukudzidza kwe enzyme kinetics.
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5′-Deoxy-5-fluorocytidine CAS:66335-38-4
5′-Deoxy-5-fluorocytidine imhando ye nucleoside analog yakagadzirwa iri kuongororwa kuti inogona kushanda sei kurwisa mavhairasi, kunyanya kurwisa mavhairasi eRNA akadai se hepatitis C virus (HCV) uye flaviviruses. Inoshanda nekuvhiringidza kudzokororwa kwemajini evhairasi, zvichizopedzisira zvaita kuti vhairasi isakwanise kuwanda nekupararira mumuviri.
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Cytidine-5′-triphosphate (CTP), disodium salt CAS:652154-13-7
Cytidine-5′-triphosphate (CTP), disodium salt i nucleoside triphosphate inoshanda sechivako chekugadzira RNA. Inoita basa rakakosha mu metabolism yemasero uye yakakosha pakutamiswa kwemashoko e genetic kubva kuDNA kuenda kuRNA panguva yekunyorwa. CTP inoshandiswa zvakanyanya mukutsvagisa kwe molecular biology, kunyanya muzvidzidzo zvine chekuita nekugadzirwa kweRNA, kupindira kweRNA, uye mamwe maitiro ane chekuita neRNA. Pamusoro pezvo, inoshandiswa mukuita kwe enzyme, zvidzidzo zve nucleotide metabolism, uye se substrate yekuongorora kwakasiyana-siyana kwe biochemical. Muindasitiri yemishonga, CTP inogona zvakare kushandiswa mukugadzira mishonga ye antiviral uye anticancer.
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ITP, inosine 5′-triphosphate trisodium munyu CAS:35908-31-7
Munyu weInosine-5′-triphosphate trisodium, unowanzo pfupikiswa seITP-Na3, imhando yeinosine yetriphosphate, nucleoside inoita basa rakakosha mumabasa akasiyana-siyana ehupenyu. Musanganiswa uyu imhando yemunyu, zvichiita kuti unyungudike mumvura uye wakakodzera kushandiswa mukuongorora biochemical uye enzyme, pamwe nekutsvaga molecular biology. Munyu weInosine-5′-triphosphate trisodium unoshandiswa pakudzidza maitiro enzymatic, nucleotide interconversion, uye se substrate yemamwe ma enzymes. Mashandisirwo awo anosvikawo kuzvidzidzo zve analog nucleotide uye sechikamu chekugadzirira misanganiswa ye nucleotide inoshandiswa muhunyanzvi hwe molecular biology.
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5-Bromouracil CAS: 51-20-7 Mutengo wemugadziri
5-Bromouracil imhando yeuracil yakagadzirwa, inova chikamu cheRNA. 5-Bromouracil inogona kuiswa mu nucleic acids uye inogona kukonzera shanduko dzemuviri nekukanganisa guanine panguva yekudzokororwa kweDNA. Inoshandiswa semutagen mukutsvagisa majini kudzidza mwero wekushanduka kwemuviri uye mashandiro awo.
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5-Fluoro-2′-deoxyuridine CAS:50-91-9
5-Fluoro-2′-deoxyuridine imhando ye nucleoside analog inodzivisa kugadzirwa kweDNA. Yakaongororwa kuti inogona kuva nehutachiona hwehutachiona uye inodzivirira bundu. Pamusoro pezvo, inoshandiswa sechishandiso chekutsvagisa mu molecular biology ne biochemistry.
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Cytidine-5′-triphosphate disodium munyu CAS:36051-68-0
Cytidine-5′-triphosphate disodium salt (CTP-Na2) i nucleoside triphosphate inoshanda sechivharo chekuvaka mukugadzirwa kweRNA. Inoita basa rakakosha mukushandiswa kwemasero, ichishanda se substrate yeRNA polymerases mu transcription uye senzvimbo yesimba yemaitiro akasiyana-siyana e enzyme. CTP-Na2 inowanzoshandiswa mukutsvagisa biochemical uye molecular biology sechikamu chemaitiro anosanganisira kugadzirwa kweRNA, kugadziriswa, uye kurongeka. Munyu wayo we disodium unowedzera kunyungudika kwayo mumvura, zvichiita kuti ive nyore kushandiswa murabhoritari.
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Ribonucleic acid kubva kuBaker's Yeast CAS:63231-63-0
Ribonucleic acid (RNA) inobva kuBaker's yeast, inozivikanwawo seSaccharomyces cerevisiae, inoreva mamorekuru eRNA ari mufungus iyi ine cell imwe chete. Inoshanda mabasa akasiyana-siyana akakosha musero, kusanganisira kugadzira mapuroteni, enzyme activity, uye gene regulation. RNA inobva kuBaker's yeast inofarira masayendisiti nevaongorori vanodzidza nezve molecular biology, genetics, uye cellular processes. Inoshandiswa mukuyedza kwakasiyana-siyana nezvidzidzo kuti vawane ruzivo rwemagene expression, RNA processing, uye mamorekuru mashandiro ari pasi pema cell functions.
