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Amlodipine Base CAS: 88150-42-9
Amlodipine Base mushonga une simba rekudzivirira calcium channel unoshandiswa zvakanyanya mukurapa BP uye angina pectoris. Kushanda kwayo mukurapa kunosanganisira kudzivirira kupinda kwecalcium ion mutsandanyama dzakatsetseka dzeropa nenyama yemwoyo, zvichikonzera kuyerera kweropa uye kudzikira kwekuda kwemoyo. Kugara kwenguva refu kweAmlodipine kunoita kuti mushonga uyu upihwe kamwe chete pazuva, zvichiwedzera kutevedzera mirairo yekurapa. Semushonga we dihydropyridine, unobvumirwa zvakanaka, uye une hutano hwakanaka. Mushonga uyu wave mushonga unokosha mukurapa kwemwoyo nekuda kwekushanda kwawo mukuvandudza mhedzisiro yekiriniki yevarwere vane matambudziko akasiyana-siyana emwoyo.
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2-Methoxyphenylacetone CAS:5211-62-1
2-Methoxyphenylacetone iketone inonhuhwirira inosiyaniswa neboka remethoxy rakabatana nephenyl ring neboka rinoshanda reacetone. Mushonga uyu wakwezva kutariswa kwekushandiswa kwawo mukugadzirwa kweorganic uye semorekuru inogona kushanda mumakemikari ekurapa. Kuvapo kwemethoxy substituent kunowedzera kunyungudika kwayo uye reactivity, zvichiita kuti ive chivakwa chinoshanduka-shanduka chekugadzira zvivakwa zvakaoma. Tsvagiridzo yatanga kuongorora mabasa ehupenyu ane chekuita ne2-methoxyphenylacetone, zvichiratidza kushandiswa kunogona kuitwa mumishonga, kunyanya muminda yemishonga inoderedza kuzvimba uye inonyaradza marwadzo.
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1-Methylindazole-3-carboxylic acid CAS:50890-83-0
1-Methylindazole-3-carboxylic acid imhando yeorganic inozivikanwa nemabasa ayo ekugadzira mishonga uye kushandiswa kwayo kwakasiyana-siyana mumakemikari ekurapa. Iyi makemikari ine chimiro cheindazole chine boka remethyl uye boka recarboxylic acid, izvo zvinobatsira mukuita kwayo makemikari uye zvinogona kurapa. Yakawana kufarira kwebasa rayo sechivako mukugadzirwa kwemishonga yakasiyana-siyana uye makemikari ekurima. Hunhu hwakasiyana hwe1-methylindazole-3-carboxylic acid hunoibvumira kutora chikamu mumaitiro akasiyana-siyana emakemikari, zvichiita kuti ive chinangwa chakakosha kune vaongorori vanoongorora mishonga mitsva.
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2-Bromophenylacetone CAS:21906-31-0
2-Bromophenylacetone iketone inonhuhwirira ine bromine substituent iri panzvimbo ye phenyl ring, pamwe chete neboka re acetone functional. Mushonga uyu wakawana kufarira kukuru mukugadzirwa kwe organic uye medical chemistry nekuda kwekushanda kwawo sechivako chinoshanduka-shanduka chekugadzirwa kwemamorekuru akaomarara, kusanganisira mishonga yakasiyana-siyana. Kuvapo kweatomu ye bromine kunowedzera electrophilic reactivity, zvichiita kuti makemikari awedzere kushanduka. Pamusoro pezvo, 2-bromophenylacetone inogona kuratidza mabasa anozivikanwa e biological, zvichiita kuti ive nyaya yekutsvagisa kwezvinogona kushandiswa pakurapa munzvimbo dzakadai semishonga inorwisa utachiona uye inorwisa kuzvimba.
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BOC-SER(ME)-OH CAS:51293-47-1
BOC-SER(ME)-OH, kana kuti tert-butyloxycarbonyl-serine methyl ester, chinhu chinodzivirira amino acid chinowanzo shandiswa mukugadzirwa kwepeptide uye makemikari ekurapa. Boka reBOC (tert-butyloxycarbonyl) rinoshanda sechikamu chinodzivirira, richibatsira kusarudza kweboka reamino panguva yekuumbwa kwepeptide, nepo serine residue ichibatsira mukusiyana kwema peptide nemapuroteni. Maumbirwo akasiyana ekomponendi iyi anoita kuti ive chinhu chakakosha mukugadzirwa kwema peptides nemishonga inoshanda, kunyanya ayo anotarisa nzira dzakasiyana dzehupenyu. Kushandiswa kwayo mukugadzirwa kwepeptide yakasimba kunowedzera kusimbisa kukosha kwayo mumakemikari emazuva ano eorganic.
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5-Bromo-7-azaindole CAS:183208-35-7
5-Bromo-7-azaindole ikemikari ine nitrogen ine heterocyclic iri mumhuri yeindole, inonyanya kuzivikanwa nekubatanidzwa kweatomu yebromine neatomu yenitrogen muchimiro chayo cherin'i. Kemikari iyi yakawana kufarira mumakemikari ekurapa nekuda kwemabasa ayo ehupenyu, kusanganisira simba rekudzivirira bundu uye hutachiona. Kutsiva kwe7-aza kunobvumira kudyidzana kwakasiyana nezvinangwa zvehupenyu, zvingangokanganisa kudzivirira enzyme uye kubatana kwema receptor. Sezvo vaongorori vachiramba vachiongorora mashandisirwo ayo, 5-bromo-7-azaindole inomiririra chigadziko chinovimbisa chekugadzirwa kwemishonga mitsva yakanangana nekurapa zvirwere zvakasiyana-siyana.
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5-Acetonyl-2-methoxybenzene sulfonamide CAS:116091-63-5
5-Acetonyl-2-methoxybenzene sulfonamide chinhu chinowanikwa mu organic chinozivikanwa nekushanda kwayo kwe sulfonamide uye chimiro chayo chezvinonhuwira zvakasiyana. Chinhu ichi chine methoxy group, acetonyl substituent, uye sulfonamide moiety, iyo inobatsira mumhando dzakasiyana dzemakemikari ayo uye mabasa ayo ehupenyu. Sulfonamides yagara ichizivikanwa nekuda kwesimba rayo rekuuraya utachiona, nepo chimiro che 5-acetonyl-2-methoxybenzene sulfonamide chinogona kuwedzera reactivity yayo uye pharmacological profile. Sezvo vaongorori vachiongorora kugadzirwa kwayo uye mashandisirwo ayo, chinhu ichi chave chiri mukana wekubudirira mu chemistry yemishonga, kunyanya mukugadzira mishonga mitsva yekurapa.
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2-Amino-2-ethyl-1,3-propanediol CAS:115-70-8
2-Amino-2-ethyl-1,3-propanediol, inowanzonzi AEPD, iamino alcohol ine branched-chain inozivikanwa nekuvapo kwemapoka emaamino nehydroxyl anoshanda. Musanganiswa uyu une chimiro chakasiyana chinowedzera kunyungudika kwayo uye reactivity yayo munzvimbo dzakasiyana dzemakemikari. Inozivikanwa nebasa rayo sebuffering agent uye chinhu chakakosha mukugadzirwa kweorganic. Nekuda kwehunhu uhwu, AEPD yakwezva kutariswa mukugadzirwa kwemishonga, kutsvagisa kwebiochemical, uye mafomura ekushongedza.
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1-TERT-BUTOXY-2-PROPANOL CAS:57018-52-7
1-Tert-butoxy-2-propanol idoro rechitatu rinozivikanwa nekuvapo kweboka retert-butoxy uye musana wepropanol. Musanganiswa uyu unoratidza hunhu hwakafanana nehwemaalcohols, senge kunyungudika kwakanaka muzvinhu zvinonyungudutsa zve organic uye polarity iri pakati nepakati. Maumbirwo awo akasiyana anoupa reactivity chaiyo, zvichiita kuti ushande se solvent uye reagent mumaitiro akasiyana emakemikari. Vaongorori nemaindasitiri vanokoshesa musanganiswa uyu nekuda kwekushanda kwawo kwakasiyana-siyana mukushandiswa kwemakemikari e organic synthesis uye formulation.
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Bis(neopentyl glycolato)diboron CAS:201733-56-4
Bis(neopentyl glycolato)diboron iboka re organoboron rinozivikanwa ne neopentyl glycolate ligands mbiri dzakasanganiswa ne central diboron unit. Iri boka rinokosheswa nekuda kwehunhu hwaro hwemakemikari hwakasiyana, kusanganisira kugona kwaro kushanda se reagent mumaitiro akasiyana emakemikari. Maumbirwo aro anoribvumira kutora chikamu mukuchinja-chinja kuri kuitwa ne boron, zvichiita kuti rive pakati pe synthetic organic chemistry. Nekuda kwekuvapo kwe glycolate moiety, boka iri rinozivikanwawo nekunyungudika kwaro mu polar solvents uye kuenderana nemapoka akasiyana-siyana anoshanda, zvichibatsira mukushandiswa kwaro mumhando dzakasiyana.
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2-BENZYLOXY-1,3-PROPANEDIOL CAS:14690-00-7
2-Benzyloxy-1,3-propanediol chinhu chinowanikwa mumakemikari ane benzyloxide group yakabatana nekabhoni yechipiri yepropanediol structure. Chinhu ichi chinoratidzwa nehunhu hwacho hwechiral uye kushanda kwakawanda, zvichiita kuti chive chinhu chakakosha mukugadzirwa kwemakemikari echisikigo uye kemikari yekurapa. Kuvapo kwechikamu chebenzylyl kunosimudzira kunyungudika uye reactivity yemorekuru, zvichibatsira mukushandiswa kwayo mukugadzira maumbirwo akaomarara emakemikari ekushandisa mumishonga.
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2-Methylene-1,3-propanediol CAS:3513-81-3
2-Methylene-1,3-propanediol ikemikari inoratidzwa nechimiro chayo chakasiyana, chinosanganisira boka re methylene ne hydroxyl. Kemikari iyi inozivikanwa nekuita kwayo se vinyl alcohol derivative, zvichiita kuti ive chinhu chakakosha mukugadzirwa kwe organic. Hunhu hwayo hunogona kushandiswa zvakasiyana-siyana, zvichiita kuti pave nekushanduka-shanduka kwemakemikari akasiyana-siyana, zvichiita kuti mamwe mamorekuru akaomarara awedzere kukura. Nekuda kwehunhu uhwu, 2-methylene-1,3-propanediol inoshandiswa munzvimbo dzakasiyana-siyana, kusanganisira mishonga, sainzi yezvinhu, uye polymer chemistry.
