Fmoc-Asn(Trt)-OH CAS:132388-59-1

Fmoc-Asn(Trt)-OH ine chinzvimbo chikuru mukuumbwa kwepeptide, kunyanya mukuunganidzwa kwakadzorwa kwepeptides dzine asparagine. Boka rinodzivirira Fmoc rinodzivirira boka reamino, richivimbisa kuti pane zvinoitwa panguva yekubatanidza peptide, nepo boka retrityl richipa dziviriro yakawedzerwa. Vaongorori vanoshandisa zvakanyanya Fmoc-Asn(Trt)-OH mukuumbwa kwepeptides mukushandiswa kwakasiyana-siyana, kusanganisira kugadzira mishonga, biomaterials, uye dhizaini yebioactive peptides. Kuenderana kwayo nemaitiro akajairwa ekugadzira peptide, ese ari maviri mumatanho echikamu chakasimba uye echikamu chemhinduro, kunowedzera kushanda kwayo mumabasa akasiyana-siyana ekutsvagisa. Kubviswa kwakadzorwa kwemapoka anodzivirira kunobvumira kuiswa kweasparagine muzvikamu zvepeptide, zvichibatsira mukusiyana kwemapeptides anogona kugadzirwa. Uyezve, Fmoc-Asn(Trt)-OH inowana kushanda mukugadzirwa kwemapeptides ekutsvagisa kweproteomics uye kudzidza maitiro emasero. Kushandiswa kweboka rekudzivirira retrityl kunogonesa kushandiswa kwakarurama kwe asparagine reactivity, zvichipa vaongorori chishandiso chakakosha chekugadzira mapeptide ane shanduko dzakati. Mukupfupisa, Fmoc-Asn(Trt)-OH inomira sechishandiso chinoshandiswa zvakasiyana-siyana uye chisingakoshi mu peptide chemistry, ichipa vaongorori simba rekuongorora nekugadzirisa asparagine reactivity kune akasiyana mashandisirwo esainzi.