Fmoc-D-Asp(OBut)-OH CAS:112883-39-3

Fmoc-D-Asp(OBut)-OH inoshanda sechinhu chakakosha mukugadzirwa kwepeptide, kunyanya mukugadzira mapeptide ane D-enantiomer yeaspartic acid nemazvo. Boka rinodzivirira Fmoc rinodzivirira boka reamino, richivimbisa maitiro akasarudzwa panguva yekubatana kwepeptide, nepo boka reO-butyl richiwedzera imwe layer yekudzivirira kuboka recarboxyl. Vaongorori vanoshandisa zvakanyanya Fmoc-D-Asp(OBut)-OH mukugadzira mapeptide ekushandisa akasiyana-siyana, kusanganisira kugadzira mishonga, biomaterials, uye kugadzira mapeptide anoshanda ane chimiro chakananga. Kuenderana kwayo nemaitiro akajairwa ekugadzira peptide, mune ese ari maviri solid-phase uye solution-phase strategies, kunowedzera kushanduka kwayo mumabasa akasiyana-siyana ekutsvagisa. Kubviswa kwakadzorwa kwemapoka anodzivirira kunobvumira kuiswa kweD-aspartic acid mu peptide sequences, kuwedzera huwandu hwemapeptide anogona kugadzirwa. Uyezve, Fmoc-D-Asp(OBut)-OH inowana rubatsiro mukugadzira mapeptide ekutsvaga maproteomics nekudzidza maitiro emasero. Kushandiswa kweboka rekudzivirira reO-butyl kunogonesa kushandiswa kwakarurama kweD-aspartic acid reactivity, zvichipa vaongorori chishandiso chakakosha chekugadzira mapeptide ane shanduko dzakagadzirirwa ivo. Mukupfupisa, Fmoc-D-Asp(OBut)-OH inomira sechishandiso chinoshandiswa zvakasiyana-siyana uye chisingakoshi mu peptide chemistry, ichipa vaongorori simba rekuongorora nekugadzirisa D-aspartic acid reactivity kune akasiyana mashandisirwo esainzi, kunyanya kutarisa mapeptide ane iyi amino acid inokosha.