Fmoc-Asp(OBzl)-OH CAS:86060-84-6

Fmoc-Asp(OBzl)-OH inoita basa rakakosha mukugadzirwa kwepeptide, kunyanya mukugadzira mapeptide ane aspartic acid nemazvo. Boka rinodzivirira Fmoc rinodzivirira boka reamino, richivimbisa kuti pane zvinoitwa panguva yekubatanidza peptide, nepo boka rebenzyl richiwedzera dziviriro yakawedzerwa kuboka recarboxyl. Vaongorori vanoshandisa zvakanyanya Fmoc-Asp(OBzl)-OH mukugadzira mapeptide ekushandisa akasiyana-siyana, kusanganisira kugadzira mishonga, biomaterials, uye kugadzira mapeptide anoshanda ane chimiro chakananga. Kuenderana kwayo nemaitiro akajairwa ekugadzira peptide, mune ese ari maviri solid-phase uye solution-phase strategies, kunowedzera kushanduka kwayo mumabasa akasiyana-siyana ekutsvagisa. Kubviswa kwakadzorwa kwemapoka anodzivirira kunobvumira kuiswa kweaspartic acid mu peptide sequences, kuwedzera huwandu hwemapeptide anogona kugadzirwa. Uyezve, Fmoc-Asp(OBzl)-OH inowana rubatsiro mukugadzira mapeptide ekutsvaga maproteomics nekudzidza maitiro emasero. Kushandiswa kweboka rekudzivirira benzyl kunogonesa kushandiswa kwakanyatsojeka kweaspartic acid reactivity, zvichipa vaongorori chishandiso chakakosha chekugadzira mapeptide ane shanduko dzakagadzirirwa ivo. Mukupfupisa, Fmoc-Asp(OBzl)-OH inomira sechishandiso chinoshandiswa zvakasiyana-siyana uye chisingakoshi mu peptide chemistry, ichipa vaongorori simba rekuongorora nekugadzirisa aspartic acid reactivity kune akasiyana mashandisirwo esainzi, kunyanya kutarisa mapeptide ane iyi amino acid inokosha.