H-Glu-OBzl CAS:13030-09-6

H-Glu-OBzl inoshanda sechivharo chakakosha mukugadzirwa kwepeptide, zvichibvumira shanduko yeglutamic acid residues mukati mepeptides. Kushanda kwebenzyl ester kunoita kuti glutamic acid side chains ishande zvakanaka, zvichigonesa kugadzirira mapeptides akagadziriswa ekuongorora kupindirana kwemaprotein, receptor-ligand binding, uye hukama hwechimiro nemabasa. Pamusoro pezvo, iyi compound inoshandiswa mukugadzirwa kwepeptide yakasimba, ichibatsira mukugadzirwa kwemapeptide matsva ane hunhu hwakagadzirirwa uye mashandisirwo anogona kushandiswa pakurapa. Uyezve, H-Glu-OBzl inotsigira tsvakiridzo yakanangana nekunzwisisa basa reglutamic acid mumaitiro ehupenyu nekugadzirwa kwemishonga. Inogonesa masayendisiti kuongorora kukanganisa kwemaresidues eglutamic acid akagadziriswa pachimiro nekushanda kwepeptide, zvichibatsira mukufambira mberi mukurapa kwakavakirwa papeptide uye kuwanikwa kwemishonga. Kushanda kwayo kunosvika pakuferefeta mu enzyme, neurobiology, uye sainzi yezvinhu, zvichipa ruzivo rwakakosha mukushanda kwakasiyana-siyana kwemapeptides ane maresidues eglutamic acid akagadziriswa. Kazhinji, H-Glu-OBzl inomira sechishandiso chakakosha, ichipa simba vaongorori kuti vaongorore kuoma kwemakemikari epeptide uye zvazvinoreva pakutsvagisa kwezvekurapa uye kupindira mukurapa. Nekushandiswa kwayo kwakasiyana-siyana mukutsvagisa kwepeptide, reagent iyi ine kukosha kukuru mukusimudzira ruzivo rwesainzi uye kubatsira mukuvandudzwa kwemishonga nezvinhu zvakagadzirwa nepeptide.