Sitagliptin Phosphate CAS:654671-78-0 Mugadziri weMugadziri

Sitagliptin Phosphate inhibitor ye trizolopyrazine dipeptidyl peptidase IV. Sitagliptin ichangobva kubvumidzwa kurapa chirwere cheshuga cherudzi rwechipiri. Sitagliptin phosphate imishonga inhibitor ye dipeptidyl peptidase Ⅳ(DDP-4) yakagadzirwa nekambani yeGerman Merck uye yakatanga yawana mvumo yeUS Food and Drug Administration yekurapa chirwere cheshuga cherudzi rwechipiri, mushonga mutsva wekurwisa chirwere cheshuga, unogona kuvandudza kugona kwemuviri kuderedza huwandu hweshuga muropa, uye kuwedzera kwe incretin kunoitika zvakasikwa nekudzivisa kushanda kwe enzyme iyi, kusanganisira huwandu hweglucagon-like peptide 1 uye glucose-dependent insulinotropic peptide, nokudaro zvichikonzera kuti pancreas ivandudze kugadzirwa kwe insulin uye kumisa kugadzirwa kweshuga muchiropa, uye pakupedzisira kuderedza mhedzisiro yekiriniki yehuwandu hweshuga muropa.