FmFmoc-Asp-OBut CAS:129460-09-9

Fmoc-Asp-OBut inoshanda sechishandiso chakakosha mukugadzirwa kwepeptide, kunyanya mukugadzira mapeptide ane aspartic acid nemazvo. Boka rinodzivirira Fmoc rinodzivirira boka reamino, richivimbisa maitiro akasarudzwa panguva yekubatanidza peptide, nepo boka reO-butyl richiwedzera imwe layer yekudzivirira kuboka recarboxyl. Vaongorori vanoshandisa zvakanyanya Fmoc-Asp-OBut mukugadzira mapeptide ekushandisa akasiyana-siyana, kusanganisira kugadzira mishonga, biomaterials, uye kugadzira mapeptide anoshanda ane chimiro chakananga. Kuenderana kwayo nemaitiro akajairwa ekugadzira peptide, mune ese ari maviri solid-phase uye solution-phase strategies, kunowedzera kushanduka kwayo mumabasa akasiyana-siyana ekutsvagisa. Kubviswa kwakadzorwa kwemapoka anodzivirira kunobvumira kuiswa kweaspartic acid mu peptide sequences, kuwedzera huwandu hwemapeptide anogona kugadzirwa. Uyezve, Fmoc-Asp-OBut inowana rubatsiro mukugadzira mapeptide ekutsvaga maproteomics nekudzidza maitiro emasero. Kushandiswa kweO-butyl protection group kunogonesa kushandiswa kwakarurama kweaspartic acid reactivity, zvichipa vaongorori chishandiso chakakosha chekugadzira mapeptide ane shanduko dzakagadzirirwa ivo. Mukupfupisa, Fmoc-Asp-OBut inomira sechishandiso chinoshandiswa zvakasiyana-siyana uye chisingakoshi mu peptide chemistry, ichipa vaongorori simba rekuongorora nekugadzirisa aspartic acid reactivity kune akasiyana mashandisirwo esainzi, kunyanya kutarisa mapeptide ane iyi amino acid inokosha.