Fmoc-Arg(Tos)-OH CAS:83792-47-6

Fmoc-Arg(Tos)-OH inoita basa rakakosha mukugadzirwa kwepeptide, kunyanya kana kuchengetedzwa kwakanyatsojeka kweguanidine nitrogen muarginine kuchidikanwa. Boka rinodzivirira Fmoc rinodzivirira boka reamino, richiona kuti peptide inosanganiswa, nepo boka retosyl riri paguanidine nitrogen richipa dziviriro yakawedzerwa. Vatsvaguri vanoshandisa Fmoc-Arg(Tos)-OH pakugadzira mapeptide ane guanidine modifications chaiyo, zvichikanganisa mabasa avo ehupenyu. Nzira yekudzivirira miviri inobvumira kugadziriswa kweguanidine reactivity, zvichiita kuti iyi compound ive yakakosha mukugadzira mapeptide ezvidzidzo zveantimicrobial, bioconjugation, uye medical chemistry. Kuenderana kweFmoc-Arg(Tos)-OH nenzira dzakajairwa dzekugadzira peptide, kusanganisira solid-phase peptide synthesis (SPPS), kunowedzera kushanda kwayo. Iyi compound inoshandiswa mukuvaka mapeptide ekuongorora biological, kuwanikwa kwemishonga, uye kugadzirwa kwezvinhu zvakagadzirwa nepeptide. Kubviswa kwemapoka ekudzivirira kwakadzorwa kunobvumira kuiswa kwearginine neguanidine yakagadziriswa, zvichibatsira mukusiyana kwemapeptide anogona kugadzirwa. Mukupfupisa, Fmoc-Arg(Tos)-OH inomira sechishandiso chakasarudzika uye chinoshanda zvakasiyana-siyana mumakemikari epeptide, ichipa simba vaongorori kuti vaongorore uye vagadzirise reactivity yeguanidine kune akasiyana mashandisirwo esainzi nekurapa.