Fmoc-D-Asn(Trt)-OH CAS:180570-71-2

Fmoc-D-Asn(Trt)-OH inobatsira zvikuru mukugadzirwa kwepeptide, kunyanya mukugadzira mapeptide ane D-enantiomer yeasparagine nemazvo. Boka rinodzivirira Fmoc rinodzivirira boka reamino, richivimbisa kuti pane zvinoitwa panguva yekubatanidza peptide, nepo boka retrityl richiwedzera dziviriro yakawedzerwa. Vaongorori vanoshandisa Fmoc-D-Asn(Trt)-OH zvakanyanya mukugadzira mapeptide ekushandisa akasiyana-siyana, kusanganisira kugadzira mishonga, biomaterials, uye kugadzira mapeptide anoshanda ane stereochemical configurations chaiwo. Kuenderana kwayo nemaitiro akajairwa ekugadzira peptide, mune ese ari maviri solid-phase uye solution-phase strategies, kunowedzera kushanduka kwayo mumabasa akasiyana-siyana ekutsvagisa. Kubviswa kwakadzorwa kwemapoka anodzivirira kunobvumira kuiswa kweD-asparagine mu peptide sequences, kuwedzera repertoire yemapeptide anogona kugadzirwa. Uyezve, Fmoc-D-Asn(Trt)-OH inowana rubatsiro mukugadzira mapeptide ekutsvaga maproteomics nekudzidza maitiro emasero. Kushandiswa kweboka rekudzivirira retrityl kunogonesa kushandiswa kwakarurama kweD-asparagine reactivity, zvichipa vaongorori chishandiso chakakosha chekugadzira mapeptide ane shanduko dzakagadzirirwa ivo. Mukupfupisa, Fmoc-D-Asn(Trt)-OH inomira sechishandiso chinoshandiswa zvakasiyana-siyana uye chisingakoshi mu peptide chemistry, ichipa vaongorori simba rekuongorora nekugadzirisa D-asparagine reactivity kune akasiyana mashandisirwo esainzi, kunyanya kutarisa mapeptide ane D-amino acids.