Fmoc-Asp(OBut)-OH CAS:71989-14-5

Fmoc-Asp(OBut)-OH chishandiso chinoshanda zvakasiyana-siyana mukugadzira mapeptide, kunyanya mukugadzira mapeptide ane aspartic acid nemazvo. Boka rinodzivirira reFmoc rinodzivirira boka reamino, richivimbisa kuti pane zvinoitwa panguva yekubatanidza mapeptide, nepo boka reO-butyl richiwedzera dziviriro yakawedzerwa kuboka recarboxyl. Vaongorori vanoshandisa zvakanyanya Fmoc-Asp(OBut)-OH mukugadzira mapeptide ekushandisa akasiyana-siyana, kusanganisira kugadzira mishonga, biomaterials, uye kugadzira mapeptide anoshanda ane chimiro chakananga. Kuenderana kwayo nemaitiro akajairwa ekugadzira mapeptide, mune ese ari maviri solid-phase uye solution-phase strategies, kunowedzera kushanduka kwayo mumabasa akasiyana-siyana ekutsvagisa. Kubviswa kwakadzorwa kwemapoka anodzivirira kunobvumira kuiswa kweaspartic acid muzvikamu zvepeptide, zvichiwedzera huwandu hwemapeptide anogona kugadzirwa. Uyezve, Fmoc-Asp(OBut)-OH inowana rubatsiro mukugadzira mapeptide ekutsvaga maproteomics nekudzidza maitiro emasero. Kushandiswa kweO-butyl protection group kunogonesa kushandiswa kwakarurama kweaspartic acid reactivity, zvichipa vaongorori chishandiso chakakosha chekugadzira mapeptide ane shanduko dzakagadzirirwa ivo. Mukupfupisa, Fmoc-Asp(OBut)-OH inomira sechishandiso chakakosha uye chisingakoshi mu peptide chemistry, ichipa vaongorori simba rekuongorora nekugadzirisa aspartic acid reactivity kune akasiyana mashandisirwo esainzi, kunyanya kutarisa mapeptide ane iyi amino acid inokosha.