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Amylase, a-, Aspergillus oryzae CAS:9001-19-8 Mutengo wemugadziri
Amylase ienzyme inoita kuti starch iparadzwe kuita shuga dziri nyore dzakadai semaltose neglucose. Inowanzo gadzirwa nezvinhu zvipenyu zvakasiyana-siyana, kusanganisira mabhakitiriya, fungi, nemiti.
Izwi rekuti “a-” mu “a-amylase” rinoreva rudzi rweamylase runonyanya kusanganisa ma alpha-1,4 glycosidic bonds ari mukati me starch molecule. Izvi zvinoguma nekugadzirwa kwe shorter chain polysaccharides, iyo inogona kupatsanurwa kuita glucose nemamwe ma amylase enzymes.
Aspergillus oryzae rudzi rwefungus rine filamentous rinozivikanwa nekukwanisa kwayo kugadzira amylase yakawanda. Inowanzoshandiswa mukugadzirwa kwema enzymes emaindasitiri nekuda kwebasa rayo guru re amylolytic. Ma enzymes anogadzirwa neAspergillus oryzae, anosanganisira a-amylase, anoshandiswa zvakanyanya mumaindasitiri akasiyana-siyana, akadai sekugadzira chikafu, kubika, machira, uye sipo.
Muindasitiri yezvekudya, a-amylase inobva kuAspergillus oryzae inowanzoshandiswa mukubika, kubika, uye kugadzira starch. Inobatsira kuputsa starch muhupfu, mumera, nezvimwe zvinhu zvakagadzirwa, zvichiita kuti zvive nyore kushandura makabhohaidhiretsi akaomarara kuita shuga dziri nyore dzinogona kugayiwa nembiriso kana mabhakitiriya panguva yekuvirisa. Iyi enzyme inoshandiswawo mukugadzira machira kuti zvive nyore kubvisa zvinhu zvinoumba saizi yestarch kubva mumachira.
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Aprotinin CAS:9087-70-1 Mutengo wemugadziri
Aprotinin inodzivirira ma enzymes akasiyana-siyana eproteolytic, anosanganisira trypsin, chymotrypsin, uye plasmin. Inowanzoshandiswa muzvipatara, kunyanya mukuvhiyiwa kwemwoyo, kuderedza kubuda ropa uye kuderedza kurasikirwa neropa. Aprotinin inoshanda nekudzivisa kushanda kwema enzymes aya, ayo anobatanidzwa mukuputsika kwema clots eropa uye kuora kwe fibrin, puroteni inobatsira mukugadzirwa kwema enzymes. Nekudzivirira kushanda kwakanyanya kwema enzymes, aprotinin inobatsira kuchengetedza kugadzikana kwema clots eropa, nokudaro ichideredza matambudziko ekubuda ropa panguva yekuvhiyiwa.
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Thrombin CAS:9002-04-4 Mutengo wemugadziri
Thrombin ienzyme inokosha inobatanidzwa mukugwamba kweropa, inozivikanwawo se coagulation. Inogadzirwa kubva kuproteni yayo yekutanga, prothrombin, mukupindura kukuvara kana kukuvara kwetsinga dzeropa. Thrombin inoita basa rakakosha mukuumbwa kwegwamba reropa, izvo zvinobatsira kudzivirira kubuda ropa zvakanyanya uye kukurudzira kupora kwemaronda.
Kana yangoshanda, thrombin inoshandura fibrinogen, imwe puroteni iri muropa, kuita fibrin. Fibrin inoumba chimiro chakaita semesh chinobata maplatelet nemasero matsvuku eropa, zvichiita kuti ropa rigare rakagwinha. Thrombin inomutsawo zvimwe zvinhu zvinoita kuti ropa rigwinhane, zvichiita kuti majoini awedzere.
Kupfuura basa rayo mukuumbwa kweropa rakagwamba, thrombin ine mamwe mabasa akakosha. Inokurudzira kupora kwemaronda nekukurudzira kufamba uye kuwanda kwemasero anobatanidzwa mukugadzirisa nyama. Thrombin inoshandawo semushonga wevasoconstrictor, zvichiita kuti mitsipa yeropa itete uye ideredze kuyerera kweropa kunzvimbo yakakuvara.
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Urease CAS:9002-13-5 Mutengo wemugadziri
Urease ienzyme inokonzeresa hydrolysis yeurea kuita ammonia uye carbon dioxide. Inogadzirwa netupukanana twakasiyana-siyana, kusanganisira mabhakitiriya, fungi, nemiti. Urease inokosha pakugadzirwa kwenitrogen uye inoita basa rakakosha mumabasa akasiyana-siyana ehupenyu, akadai se urea hydrolysis muitsvo uye nitrogen assimilation mumiti. Inoshandiswawo mumaindasitiri, kusanganisira kuongororwa kwebhakitiriya inogadzira urea, mafetiraiza anobva ku urea, uye kuonekwa kweurease inhibitors pakurapa mamwe mamiriro ehutano.
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Leupeptin hemisulfate CAS:103476-89-7
Leupeptin hemisulfate inodzivirira protease inowanzoshandiswa muongororo ye biochemical uye biomedical. Inobva kuStreptomyces bacteria uye inoshanda nekudzivirira mashandiro emaprotease akasiyana-siyana, anosanganisira trypsin, chymotrypsin, uye plasmin.
Leupeptin hemisulfate inowanzoshandiswa mukuyedza murabhoritari kudzivirira kuparara kwemapuroteni kusingadiwe, sezvo mapuroteni anogona kukanganisa mapuroteni nemapeptide, zvichikanganisa mhedzisiro yekuyedza. Nekudzivisa kushanda kweprotease, leupeptin hemisulfate inobatsira kudzikamisa mapuroteni uye kuchengetedza kunaka kwawo panguva yekuyedza.
Pamusoro pezvo, leupeptin hemisulfate yakashandiswa muzvidzidzo zvemaseru kuti iongorore mabasa emaprotease mumabasa akasiyana-siyana emasero, akadai sekutumira masaini emasero, apoptosis, uye kudzoka kwemapuroteni.
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Lipase kubva paganda renguruve CAS:9001-62-1
Lipase ienzyme inokonzeresa hydrolysis yemafuta, kunyanya kuputsika kwetriglycerides kuita fatty acids neglycerol. Inogadzirwa nezvinhu zvakasiyana-siyana, kusanganisira mhuka, zvirimwa, uye tupukanana. Lipase inoita basa rakakosha mukugaya, sezvo ichibatsira mukuputsika nekunyudzwa kwemafuta ekudya muura hudiki. Pamusoro pezvo, lipase ine mashandisirwo akawanda mumaindasitiri akadai sekugadzira chikafu, kugadzira sipo, mishonga, uye kugadzira biofuel. Kugona kwayo hydrolyze lipids kunoita kuti ive yakakosha pamabasa akadai sekugadzirisa lipids, kuwedzera kunaka, uye kubvisa mafuta.
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Lysostaphin CAS:9011-93-2 Mutengo wemugadziri
Lysostaphin ienzyme ine simba rekuuraya utachiona inonyanya kurwisa uye kuuraya Staphylococcus aureus, bhakitiriya rinokonzera hutachiona hwakasiyana-siyana muvanhu. Rinobva kubhakitiriya rinonzi Staphylococcus simulans uye rine simba rekuputsa madziro esero eS. aureus, zvichiita kuti riparare.
Iyi enzyme inonyanya kunanga peptidoglycan layer yemadziro esero rebhakitiriya, ichikanganisa chimiro chayo uye ichikonzera lysis yebhakitiriya. Maitiro aya akasiyana anoita kuti lysostaphin ishande zvakanyanya pakurwisa S. aureus types, kusanganisira iyo isingarapike nemishonga inowanzoshandiswa.
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L-Lactate dehydrogenase CAS:9001-60-9
L-Lactate dehydrogenase (LDH) ienzyme inoita basa guru mukushandiswa kwesimba remasero, kunyanya mukushandurwa kwepyruvate kuita lactate. Inobatsira kushandurwa kweL-lactate kuita pyruvate, ichishandisa NAD+ se cofactor.
LDH inowanikwa munyama dzakasiyana dzemuviri, kusanganisira chiropa, moyo, tsandanyama, uye masero matsvuku eropa. Kushanda kwayo kunogona kushanda sechiratidzo chezvirwere zvakasiyana, zvakaita sekukuvadzwa kwechiropa, myocardial infarction, uye mamwe marudzi ekenza.
Basa guru reLDH nderekuchengetedza kuenzana kwesimba remasero nekubatsira kushandurwa kwepyruvate, chigadzirwa cheglycolysis, kuita lactate. Maitiro aya, anozivikanwa seanaerobic glycolysis, anoitika pasina okisijeni uye anobvumira masero kuramba achigadzira simba kana okisijeni yave shoma.
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Pepsin CAS:9001-76-7 Mutengo wemugadziri
Pepsin ienzyme yekugaya inowanikwa mudumbu inoita basa guru mukugaya nekuputsa mapuroteni. Iri muboka rema enzyme anonzi proteases, ayo anokonzera kuputsa mapuroteni kuita ma peptides madiki nema amino acids, zvichiita kuti apinde muura hudiki.
Pepsin inogadzirwa uye inoburitswa nemasero ari mudumbu, anozivikanwa semasero makuru, muchimiro chisingashande chinonzi pepsinogen. Kana chikafu chikapinda mudumbu, chinoita kuti gastric acid iburitswe, iyo inoshandura pepsinogen kuita chimiro chayo chinoshanda, pepsin. Pepsin inoshanda zvakanaka munzvimbo ine acid, sezvo pH yakaderera yemudumbu ichibatsira kumutsa nekuchengetedza enzyme yayo.
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Mapuroteni Kinase Supplement KT5823 CAS:126643-37-6
Protein kinase supplement KT5823 chinhu chidiki chinodzivirira mamorekuru chinonyatsonangana nekudzivirira mashandiro eprotein kinase. Maprotein kinases maenzymes anofosfera mapuroteni nekuwedzera mapoka ephosphate kune mamwe maamino acid residues, kazhinji serine, threonine, kana tyrosine. Maitiro aya efosforlation anoita basa rakakosha munzira dzakasiyana-siyana dzekutumira masaini emasero, kudzora mashandiro eprotein, uye kudzora maitiro emasero akadai sekukura kwemasero, kupatsanurwa, kusiyanisa, uye apoptosis.
KT5823 inowanzoshandiswa muzvidzidzo zvekutsvagisa kuti iongorore mashandiro uye nzira dzekuzivisa mapuroteni kinases. Nekudzivisa mapuroteni kinases, KT5823 inogona kubatsira vaongorori kuona mapuroteni chaiwo nenzira dzinokanganiswa nebasa rekinases. Ruzivo urwu runogona kubatsira mukunzwisisa basa remapuroteni kinases mumabasa emasero uye kugona kuona zvinangwa zvitsva zvekurapa.
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Pyridoxal-5′-phosphate monohydrate CAS:41468-25-1
Pyridoxal-5′-phosphate monohydrate, inozivikanwawo sePLP, ndiyo mhando inoshanda yevhitamini B6. Ndiyo coenzyme inokosha inobatanidzwa mukuita kwakasiyana-siyana kwema enzyme mumuviri. PLP inoita basa rakakosha mukugadzirwa kwemaamino acid, kugadzirwa kwema neurotransmitter, uye kugadzirwa kweheme, chikamu chehemoglobin.
PLP inoshanda se coenzyme nekusunga kune ma enzyme chaiwo uye kubatsira mukuita kwemakemikari. Inoshanda se catalyst, ichibatsira kushandurwa kwezvinhu zvakasiyana-siyana, zvakaita se amino acids, kuita zvigadzirwa zvakasiyana. PLP inonyanya kukosha mu metabolism ye amino acids, senge kushandurwa kwe tryptophan kuita serotonin, kana kuputsika kwe glycine kuita serine.
Pamusoro pebasa rayo mukushandiswa kwemaamino acid, PLP inobatanidzwawo mukugadzirwa kwema neurotransmitters akadai se dopamine, norepinephrine, uye gamma-aminobutyric acid (GABA). Aya ma neurotransmitters akakosha pakushanda zvakanaka kwehuropi uye anobatanidzwa mukudzora mafungiro, kuziva, uye kutapurirana kwemashoko pakati pemasero etsinga.
Uyezve, PLP inodiwa pakugadzirwa kweheme, chikamu chehemoglobin chinowanikwa mumasero matsvuku eropa. Hemoglobin ine basa rekutakura okisijeni mumuviri wese, zvichiita kuti PLP ive yakakosha pakuchengetedza mwero weokisijeni wakajairwa uye kuona kushanda zvakanaka kwenhengo dzakasiyana siyana nematishu.
Nekuda kwekukosha kwayo mumabasa akasiyana-siyana emakemikari, kuwedzerwa kwePLP dzimwe nguva kunokurudzirwa kune vanhu vane mamwe matambudziko ehutano kana kushomeka kwevhitamini B6. Inowanikwa muchimiro chekuwedzera uye inogona kunyorerwa nevanopa hutano zvichienderana nezvinodiwa.
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Kuderedza, glutathione CAS:9001-48-3
Glutathione reductase ienzyme inoita basa guru mukuchengetedza kuenzana kwe glutathione (GSH/GSSG) mumasero. Glutathione imhando ye tripeptide inoumbwa nemaamino acids glycine, cysteine, uye glutamate. Inoshanda se antioxidant huru mumasero uye inobatanidzwa mumabasa akasiyana-siyana emasero, anosanganisira kubvisa chepfu mumuviri, kugadzira DNA nekugadzirisa, uye kugadzira mapuroteni.
Glutathione reductase inoderedza oxidized glutathione (GSSG) kusvika pachimiro chayo chakaderedzwa (GSH) nekushandisa NADPH (nicotinamide adenine dinucleotide phosphate) se cofactor. Kuita uku kwakakosha pakuchengetedza mamiriro ekudzikira kwe glutathione mumasero, sezvo GSSG inogona kuungana kana paine oxidative stress.
Nekuchengetedza chiyero chakakodzera cheGSH kuGSSG, glutathione reductase inobatsira kudzivirira masero kubva mukukuvadzwa kwe oxidative kunokonzerwa ne reactive oxygen species (ROS) nemamwe mamorekuru anokuvadza. Inoshanda semutambi mukuru mukudzivirira kwemasero kwe antioxidant.
Uyezve, glutathione reductase inobatanidzwawo mukugadzirisa glutathione disulfide (GSSG) inogadzirwa panguva dzakasiyana-siyana dzekugadzirisa masero, zvichiita kuti glutathione (GSH) iwanikwe nekuda kwemabasa ayo akawanda emasero.
